Platelet Rich Plasma
Based on Image from: Louisa Howard (PD)
PRP is an autologous concentration of platelets in a small volume of plasma taken from a patient’s own blood. This plasma fraktion contains a high concentration of thrombocytes and is used for a large variety of clinical applications in the regenerative medicine.
Studies indicate that platelets contain over 400 growth factor components and cytokines that are crucial in soft tissue healing and bone regeneration – and affect inflammation, wounds, muscle tears and infection. Research shows that platelets also release many bioactive proteins responsible for attracting macrophages, mesenchymal stem cells and osteoblasts that not only promote removal of degenerated and necrotic tissue, but also enhance tissue regeneration and healing.
Recently, there has been emerging literature and evidence on the beneficial effects of Platelet Rich Plasma (PRP) for acute and chronic non-healing tendon injuries including lateral epicondylosis, plantar fasciopathy and cartilage degeneration, osteoarthritis of the knee, shoulder, hip and spine, tennis, elbow, ankle and ligament sprains.
Growth factors also play a role in signalling mesenchymal stem cells to proliferate and differentiate inside the area to be repaired. They act like “homing signals”.
Since PRP is an autologous concentration of platelets in a small volume of plasma taken from a patient’s own blood, there are no contraindications or deleterious side effects.